166TO STUDY THE PATTERN OF ANTIBIOTIC SENSITIVITY IN URINARY TRACT INFECTION AT A TERTIARY CARE CENTERUrinary tract infection is one of the most common infections occurring in all age groups. It is more common in females than men, especially in the reproductive age group of females. The presence of bacteria in urine is called bacteriuria, which may be asymptomatic or with typical symptoms of urinary tract infection like fever, burning micturition, lower abdominal pain, etc. The most common organism causing urinary tract infection is Escherichia coli, klebsiella, pseudomonas and Staphylococcus aureus. Urinary tract infection is diagnosed by urine microscopy and by culture sensitivity. Immediately after the diagnosis of urinary tract infection with urine microscopy patient is treated with blind antibiotic therapy since for the culture sensitivity result it takes 48-72 hours. The commonly used antibiotics are showing increased incidence of resistance. So this study was planned to find out the common organisms which causes urinary tract infection and the antibiotics which shows more sensitivity as well as resistant to these organisms and helps the treating doctor in selecting the antibiotics. The study was conducted in Kanyakumari government medical college, Asaripallam, by collecting the urine culture sensitivity report for 3 months (from June 2016 to august 2016) from the department of Microbiology, Kanyakumari government medical college, Asaripallam. Out of 166 urine culture sensitivity reports analyzed the most common organisms isolated were klebsiella (43.98%), Escherichia coli (36.75%), pseudomonas(7.23%) and regarding the sensivivity pattern to antibiotics, most of the uropathogens are sensitive to cefuroxime sulbactum combination (98.1%), piperacillin Tazobactam (76.5%), amikacin (65.45) and they are resistant to ampicillin (92%), cefuroxime (79.4%), amoxicillin (77.8%), gentamicin (77.8%), cephalexine (74%), ciprofloxacin (73.2%), cotrimoxazole(70.1%)vijaisundar@gmail.comResearch712017 Urinary tract infection,Culture sensitivity,AntibioticT. Ashok Kumar,E. Vijai sundar,auline Pakiaseeli,Anbarasi,MallikaProfessor & HOD, Department of Pharmacology, Kanyakumari Government Medical College, Tamilnadu, India,Assistant Professor, Department of Pharmacology, Kanyakumari Government Medical College, Tamilnadu, India.,Assistant Professor, Department of Pharmacology, Kanyakumari Government Medical College, Tamilnadu, India.,Assistant Professor, Department of Pharmacology, Kanyakumari Government Medical College, Tamilnadu, India., Tutor, Department of Pharmacology, Kanyakumari Government Medical College, Tamilnadu, India.