169EVALUATION OF ANTI DIABETIC ACTIVITY OF SELECTED PLANTS WITH INDIVIDUAL AND POLYHERBAL EXTRACTIONThe present study aimed that evaluation of anti diabetic activity of individual plants and poly herbal of all the extractions. Extraction of root and leaf of the Bauhinia rufescens Lam leaves of Cassia auriculata L, leaves and flowers of Mimosa pudica L by Maceration method. Individually and combined all the plants extracted poly herbal extraction and screened for phytochemical study performed Preliminary Phytochemical analysis of crude extracts for individual plants and poly herbal extraction for Anti-diabetic activity in Alloxan Induced Hyperglycaemic Rats, Single dose study, Multiple dose treatment. Phytochemical investigation reveals the presence of alkaloids, flavonoids, saponins, tannins, steroids, triterpinoids, carbohydrates and glycosides in poly herbal methanolic extraction and individual plant extraction, In acute toxicity studies no mortality was observed with either of the extracts even at the dose level of 2000mg/kg body weight, In the present study, the methanol extracts showed significant reduction of blood glucose levels in alloxon induced rats.srinivaskonijeti@yahoo.comResearch722017Bauhinia rufescens Lam,Cassia auriculata L,Mimosa pudica L,Anti-diabetic activitySrinivasa Rao Konijeti,G. Vidya Sagar,Sri Leela Movva Vignan Institute of Pharmceutical Sciences, Deshmukhi, Nalgonda district, Telangana, India-508284; Department of Biotechnology, Acharya Nagarjuna University, Guntur, Andhra Pradesh, India-522510.,Srinivasarao College of Pharmacy, PM Palem, Visakhapatnam, Andhra Pradesh, India- 500041.,Netaji Institute of Pharmaceutical Sciences, Nalgonda, Telangana, India-508252.