205A CASE REPORT ON CREUTZFELDT JAKOB DISEASECreutzfeldt Jakob disease (CJD) is a neurodegenerative disorder that destroys the brain cells and cause tiny holes in the brain. Damage to brain causes the mental and physical impairment associated with CJD and eventually leads to death. Here it is a case report of 61 year old female patient who was diagnosed with CJD with vocal cord paralysis. Patient with CJD will have ataxia or difficulty in controlling body movement, abnormal gait, speech and dementia. Seizure activity is a rare presentation of patient with CJD. CSF analysis, magnetic resonance imaging and electroencephalogram as well as the clinical presentation showed the evidence of CJD.arya4m@gmail.comcasereport922019Creutzfeldt Jakob disease,brain cells,mental and physical impairmentRemya Prakash,Arya M,Reshma PM, Sini SG,Dawn VJDepartment of Neurology, SK Hospital, Edappazhanji, Trivandrum-695014, Kerala, India,Department of Pharmacy Practice, Dale View College of Pharmacy and Research Centre, Punalal P.O, Poovachal, Trivandrum-695575, Kerala, India,Department of Pharmacy Practice, Dale View College of Pharmacy and Research Centre, Punalal P.O, Poovachal, Trivandrum-695575, Kerala, India,Department of Pharmacy Practice, Dale View College of Pharmacy and Research Centre, Punalal P.O, Poovachal, Trivandrum-695575, Kerala, India,Department of Pharmacy Practice, Dale View College of Pharmacy and Research Centre, Punalal P.O, Poovachal, Trivandrum-695575, Kerala, India