207PHARMACOECONOMIC ANALYSIS OF ANTIHYPERTENSIVE DRUGSClinically, hypertension may be defined as that level of blood pressure at which the institution of therapy reduces blood pressure-related morbidity and mortality. Current clinical criteria for defining hypertension generally are based on the average of two or more seated blood pressure readings during each of two or more outpatient visits. In the study two most frequently prescribed therapies, both in monothereapy and multitherapy group were compared for the cost effective ratio and quality of life. In Monotherapy group, Amlodipine is more cost effective with a mean CER of 8.93 rupees/mm of Hg whereas Atenolol group had a mean CER of 26.15 rupees/mm of Hg. Combination of Amlodipine with Enalapril was more cost effective with a mean CER of 18.24 rupees/mm of Hg as compared to combination Amlodipine with Atenolol with mean CER of 27.73 rupees/mm of Hgshujju88@gmail.comResearch922019Hypertension,CER,ICERSyed Sujat Pasha,Nayana R SakreTutor, Department of Pharmacology, Bidar Institute of Medical sciences, Bidar, Karnataka, India,Tutor, Department of Pharmacology, Mandya Institute of Medical sciences, Mandya, Karnataka, India