208EVALUATION OF QUALITY OF LIFE OF PATIENTS ON ANTIHYPERTENSIVE DRUG THERAPYDue to high prevalence of hypertension and the requirement of medications for prolonged periods, the drug treatment cost poses a major issue in health economics. In developed countries, the expenditure on antihypertensive therapy has increased sharply in recent years due to increasing use of newer and more expensive drugs. An observational comparative study was planned on 100 patients attending the outpatient Department of General medicine; Every patient had a follow up of 6 months in the study starting from the day of first data collection. In Atenolol group 100% patients had good quality of life compared to Amlodipine group which had 71.4 % patients had good, 23.8% had average and 4.8% had poor quality of life. In Amlodipine with Atenolol group nearly 88% patients had good quality , and 12% had average physical quality compared to Amlodipine with Enalapril group which had 89% in good and 11% in average physical qualityshujju88@gmail.comResearch922019Quality Of Life,Antihypertensive Drug Therapy,EnalprilSyed Sujat Pasha,Chetan DBTutor, Department of Pharmacology, Bidar Institute of Medical sciences, Bidar, Karnataka, India.,Post Graduate, Department of Pharmacology, VIMS, Ballari, Karnataka, India.