214PROFILE OF TRANSFUSION RECIPIENT IN A TERTIARY CARE CENTRE IN KANCEEPURAM DISTRICTlood transfusion is an essential practice during emergency situations as a life saving procedure done for the benefits and survival of the patient. The blood transfusion practice has the potential to save any numbers of lives every year. The process of blood transferring is done during various medical conditions like surgery, therapeutic, emergency. Prior to transferring the blood to patients, the evaluation of blood and its components are necessary for assessing the need for transfusion and also helps to avoid unnecessary reactions due to transfusion in the future. The immediate adverse reactions due to blood transfusion may involve febrile reactions, allergic reactions, anaphylactic reactions, acute hemolytic reactions (caused by transfusion of ABO incompatible blood), non-immune hemolysis (can occur due to temperature changes, mechanical forces), bacterial contamination, transfusion related acute lung injury, volume overload, hypothermia, citrate toxicity and delayed adverse effects due to transfusion are delayed hemolysis , alloimmunisation , infectious disease transmission. The study was conducted in the blood bank unit of Hematology department by the department of Pharmacology of Saveetha University in a teaching tertiary care hospital. This study utilized retrospective analysis of blood transfusion recipient’s data including all blood and blood components which was transfused within the study period of January 2018 to December 2018.Data was collected retrospectively from the register of the blood bank for the period of one year from January 2018 to December 2018 and it included all blood and blood components documented during the study period. Incompatibility occurring during transfusion was controlled by including all the necessary information such as gender, age, blood group, blood components required and clinical diagnosis. The present retrospective study has helped in identifying the need for maintaining the database in the hematology department which gives a clear idea about various blood components and blood groups transfused. The maintained record helped us in preventing various complications that occur during transfusion. The various guidelines of transfusion have also helped in reducing unnecessary health issues and economic waste in these individuals. This study also gave an insight into the judicial use of the blood component.sheelapharm15@yahoo.inResearch1012020Hemolysis,Incompatible,Transmission,Blood compoundsRoshini.S,D.Sheela,Hemamalini NV2nd year MBBS, Saveetha Medical College and Hospital, SIMATS, Chennai, India ,602105,Assistant Professor, Department of Pharmacology, Saveetha Medical College and Hospital, SIMATS, Chennai, India , 602105.,Medical Officer, Blood bank, Saveetha Medical College and Hospital, SIMATS, Chennai, India, 602105