232EVALUATION OF THE EFFICACY AND TOLERABILITY OF CEFOTAXIME AND SULBACTAM VERSUS CEFEPIME AND TAZOBACTAM IN PATIENTS WITH URINARY TRACT INFECTIONA PROSPECTIVE COMPARATIVE STUDYKlebsiella, Staphylococcus aureus, Staphylococcus saprophyticus, Proteus, Streptococcus faecalis, Streptococcus pyogenes, and Candida may all cause urinary tract infections in diabetics and immunocompromised people. Pseudomonas and Proteus are common triggers after instrumentation and catheterization. Cefotaxime is used to treat infections of the urinary tract, the lower respiratory tract, bacteremia, meningitis, uncomplicated gonorrhoea, and skin and soft tissue infections. Cefotaxime is used to treat infections of the urinary tract, lower respiratory tract, bacteremia, meningitis, uncomplicated gonorrhoea, infections of the skin and soft tissue, infections of the bone and joints, and obstetric and gynaecological infections. The current research was designed to compare the efficacy and tolerability of cefotaxime and sulbactam versus cefepime and tazobactam in patients with urinary tract infections, taking into account the aforementioned factors. When comparing the efficacy of third and fourth generation cephalosporins for clinical cure within their groups, and when comparing for intergroup efficacy, cefotaxime/sulbactam cure rates were 89.28 percent 9.1 and cefepime/tazobactam cure rates were 94.49 percent 5.06 in relieving clinical symptoms such as fever. However, one patient in group A had a positive urine culture, indicating that the pathogens had become immune and had not reacted to the therapy in these cases. Long-term studies in a larger number of patients are needed to compare efficacy, the pattern of resistance displayed by microbes to these cephalosporins, and any rare adverse effects or organ-specific toxicity and safety profiles of these drugs]]>732017Urinary Tract Infection,Inflammation,Cefepime,TazobactumPalla Raghu DeepDepartment of Respiratory Medicine, Bhaarath Medical College and Hospital, Chennai-600073, Tamil Nadu, India