257IN VITRO AND IN VIVO EVALUATION OF ANTI-DIABETIC POTENTIAL OF HEMIGRAPHIS COLORATA BLUMEThe general interest for the plants are subsequently the commencement of life which give basic wellspring of since, illnesses were brought into the world with man and prescriptions fix them since plants which deliver and contain an assortment of synthetic substances, that follow up on the body. Extraction of leaves of Hemigraphis Colorata Blume using various solvents by using Soxhlet apparatus. All the extracts on in vitro & in vivo pharmacological studies reports are positively reflexed in our research. In our findings of alfa amylase activity observation for 50 % of inhibition were found to be such as Ethyl acetate Extract 91 ?g/ml, water 80 ?g/ml, Pet.ether 75 ?g/ml and Acarbose (Positive control) 61 ?g/ml In our final report indicated that the Ethanolic extract have more anti-diabetic activity when compared to each other extract due to more anti-diabetic bioactive components present in the ethanolic extract. Finally we are concluded in this work will be useful for find the new entity for the treatment of diabetes mellitusbyjukadav@gmail. comResearch1122021Prescriptions,Hemigraphis Colorata Blume,Soxhlet apparatus,alfa amylase anti-diabetic activity and bioactive componentsByju K,Biju C.RShri Jagdish Prasad Jhabarmal Tibrewala Univerity, Jhunjhunu, Rajasthan. India,Shri Jagdish Prasad Jhabarmal Tibrewala Univerity, Jhunjhunu, Rajasthan. India