260AUTOIMMUNE MYELOFIBROSIS AS A SYMPTOM OF SYSTEMIC LUPUS ERYTHEMATOSUSBlues abnormalities in Systemic Lupus Erythematosus (SLE), including in the SLE categorization criteria, such as leucopenia, pituitary lymphopenia, thrombocytopenia and hemolytic anemia are common. While SLE can produce a range of cytopenia, autoimmune anemia (AIMF) is rare. According to cross-sectional studies, myelofibrosis is infrequent among people with SLO who have cytopenia. Two different but related disorders must be recognized between AIMF or primary immune fibrosis. In uncommon cases of AIMF in SLE which are described, AIMF tends to be present either in conjunction with SLE Diagnosis or after SLE Diagnosis. This could be because of the common symptoms of autoimmune fibrosis and SLE. It is crucial to look for autoimmune fibrosis in SLE patients that come with cytopenia and may be doing a bone marrow biopsy. This is significant since bone marrow fibrosis in SLE reacts to steroids or other immunosuppressive drugs and has a good outcome, while primary myelofibrosis is not a response to SLE standard therapy and has a less favorable outcome.babu@gmail.comResearch322013Autoimmune disease,Myelofibrosis,Systemic Lupus ErythematosusDr. D.Reddy Varaprasad babuAssistant Professor, Department of Pulmonology, Sree Lakshmi Narayana Institute of Medical Sciences, Pondicherry, India