262KNOWLEDGE AND PERCEPTION OF HEALTHCARE WORKERS AND OTHER FRONTLINE COVID WORKERS ABOUT COVID-19 VACCINATION AT A TERTIARY CARE HOSPITAL IN INDIASeveral vaccines have been approved against coronavirus disease (COVID-19) and distributed globally. However, knowledge and perception of healthcare workers and other Frontline COVID workers about COVID-19 vaccination are poorly understood. Thus, this study aimed to investigate the same at a tertiary care hospital in India. Material & Methods: A cross-sectional, observational, questionnaire-based study was conducted amongst 1550 healthcare workers and other frontline COVID workers who voluntarily agreed to participate in the study. The survey was conducted using a well-structured and self-reported questionnaire along with three sections, one each on socio-demographics, knowledge, and perception. Chi-square test was performed to determine the variables predicting knowledge and perception towards COVID-19 vaccinations. Results: Knowledge score of >=2 (out of 3) was obtained amongst 1489 (96%) while perception score of >=4 (out of 8) was found amongst 1446 (93%) of study subjects respectively. 1444 (95%) were aware of two doses of vaccination and 1124 (74%) knew about the types of vaccines available in the country. About 1443 (94%) of subjects agreed that vaccination is a necessity to end this pandemic and considered recommending the vaccine to their family members. About 1190 (80%) subjects were in favor of getting vaccinated even if it was not provided free of cost. There was no significant difference in knowledge and perception based on age and history of COVID 19. Conclusions: The findings of our study reflect adequate knowledge and positive perception towards COVID-19 vaccine amongst the healthcare workers and other frontline COVID workersshash0908@gmail.comResearch1122021Knowledge,Perception,Covid-19,Vaccine,Side EffectDr Prachi Jain,Dr Deepika Mishra,Dr Kiran Bhave,Dr Shashank Desai,Dr Prasad PanditTutor, Dept of Pharmacology, HBTMC and RNCH, Mumbai, Maharashtra, India.,Tutor, Dept of Pharmacology, GGMC and Sir JJH, Mumbai, Maharashtra, India.,Professor, Dept of Pharmacology, HBTMC and RNCH, Mumbai, Maharashtra, India.,Tutor, Dept of Pharmacology, HBTMC and RNCH, Mumbai, Maharashtra, India.,Professor and Head, Dept of Pharmacology, HBTMC and RNCH, Mumbai, Maharashtra, India.