26EVALUATION OF MIC- ANTIFUNGAL AND ANTIBACTERIAL ACTIVITIES OF MEDICINAL PLANTSThe present study was to evaluate the antifungal and antibacterial activity on nature plants. The study was on six nature plants like Sapindus emarginatus, Hibiscus rosa-sinensis, Mirabilis Jalapa, Euphorbia tirucalli L, Vitex negundo L, Saussurea Lappa Costus of Methanol, Chloroform, N-Hexane and Water extracts on various Aspergillus flavus, Candida albicans Candida glabreta, fungal strains Bacillus subtilis, Escherichia coli, Staphylococcus epidermidis bacterial strains using standard methods Agar tube dilution for antifungal, Agar diffusion assay for antibacterial as per The screening for extraction and evaluation of nature plants for anti-fungal and anti-bacterial activities for Minimum inhibitory concentration (µg/ml). Among the six plants Sapindus emarginatus, Hibiscus rosa-sinensis, Mirabilis jalapa, Euphorbia tirucalli L, Vitex negundo L, Saussurea lappa Costus used four different solvents at antimicrobial strains for antibacterial and antifungal activity it showed the best report on Sapindus emarginatus, Saussurea lappa Costus, on n-hexane extract according to Minimum inhibitory concentration leaf it showed satisfactory result against various gram +ve and gram –ve bacteria and fungi on n-hexane extract showed the highest Minimum inhibitory concentration (µg/ml) 15-18 (μg/ml) while minimum inhibitory concentration showed the lowest report then other remained crude extract Minimum Inhibitory concentration for antimicrobial activity. These results support the ethno medicinal claim for the treatment for bacterial and fungal causes of illnesses on methanol extract and on n-hexane extract at various plants according to Zone of inhibition and Minimum inhibitory concentration.rathi_sanjesh@yahoo.co.inResearch312013Minimum inhibitory concentration,Fungal Strains,Bacterial Strains,ExtractsRathi Sanjesh G,Anil Middha,Patel Kanu R Shri Jagdish Prasad Jhabarmal Tibrewala University, Vidyanagari, Jhunjhunu, Rajasthan, India, Shri Jagdish Prasad Jhabarmal Tibrewala University, Vidyanagari, Jhunjhunu, Rajasthan, India,Department of Pharmaceutics, Shri B. M. Shah College of Pharmaceutical Education and Research, Modasa, Dist-Sabarkhantha, Gujarat, India.