273DIABETES AND PREDIABETES HAVE A NEGATIVE IMPACT ON FASTING GLUCOSE AND GLUCOSE METABOLISMA statistics of first phase of a nationwide investigation in India to establish the percentage of diabetes complications (impaired glucose tolerance glucose and/or high blood sugar) are presented in this study. An stratification multistage sampling approach was used to sample adults aged 20 years in 363 primary sampling (188 urban, 175 rural) across state (Tamilnadu),. Fasting and 2 hours after carbohydrate loading serum glucose were used find out how common diabetes and prediabetes . Of the 14,277 (86 percent) of the 16,607 people who were chosen for the research took part, with 13,055 of them giving blood samples. Tamilnadu had a weighted prevalence of 10.4% diabetic (both known and diagnosed), Maharashtra had 8.4%, Jharkhand had 5.3 percent, and Chennai had 13.6 percent. Prediabetes (hyperglycaemia glucose and/or high blood sugar) was found in 8.3%, 12.8 percent, 8.1 percent, and 14.6 percent of the population, respectively. Age, male sex, impaired glucose tolerance, urban location, abdominal obesity, generalized obesity, hypertension, and financial level were all shown to be substantially linked with diabetes in a Multiple logistic regression studies were conducted. Age, diabetes during pregnancy, adiposity, hypertension, and socioeconomic level were all significant risk factors for prediabetes. According to our estimates, Maharashtra can have 6 million diabetics and 9.2 million people with prediabetes in 2011, Tamil Nadu In 2011, the United States There will be 4.8 million diabetic with 3.9 million prediabetics in the United States, 0.96 billion patients & 1.5 million prediabetics in India, and 0.12 billion diseases and 0.13 billion prediabetics in Pune. In India, diabetes affects 62.4 million people, with 77.2 billion people suffering from prediabetesRanjith@gmail.comResearch1022020Asian Indians, Diabetes, ICMR, India, PrediabetesRanjith Kumar SreeramaAssociate Professor, Department of General Medicine, Tagore Medical College & Hospital, Chennai - 600127