291ASSESSING CLINICAL COST-EFFECTIVENESS: POSTOPERATIVE CARE PATHWAY FOR MICROVASCULAR REPAIR IN HEAD AND NECK SURGERYThis study aims to assess the clinical cost-effectiveness of the postsurgical care route for patients undergoing microvascular repair after head and neck surgery. The objective is to compare outcomes between a prospective treatment group receiving clinical care after surgery and historical care groups managed before the implementation of the pathway. Effectiveness outcomes, including days in the hospital, OR visits, and ICU readmissions, were evaluated, considering the costing viewpoint of government payers. The study included 118 patients, revealing that the postoperative care route was more effective and efficient, emerging as the dominant clinical intervention. In conclusion, the implementation of a postoperative care pathway resulted in improved clinical outcomes and reduced healthcare costs for patients undergoing head and neck cancer surgery with reconstructionIndranil Mukherjee@gmail.comResearch1322023Otolaryngology,microvascular,Head and Neck Squamous Cell CarcinomaIndranil MukherjeeAssistant Professor, Department of Oto Rhino Laryngology (ENT), Gouri Devi Medical College, Rajbandh, Durgapur, West Bengal, India