<?xml version="1.0" encoding="UTF-8"?><Articles><Article><id>316</id><JournalTitle>PHYTOCHEMICAL AND PHARMACOLOGICAL EVALUATION OF ARTOCARPUS HETEROPHYLLUS LAM (JACKFRUIT) FOR ANTHELMINTIC ACTIVITY</JournalTitle><Abstract>In the current in vitro study, 10 mg/ml concentration of ethanolic extract of Artocarpus heterophyllus (A. heterophyllus)
produced a statistically significant anthelmintic activity that is comparable with the conventional anthelmintic agent,
Albendazole. This finding is additionally in line with the clinical study that confirmed the efficacy of the plant against
nematodes in calves and superior to an in vitro study that reported a moderate level of anthelmintic activity from the rind of A.
heterophyllus. A. heterophyllus, is mainly used as an anthelmintic agent in traditional practice. Concordant with this, in EHIA
of the present study, ethanolic extract of A. heterophyllus fruit induced a significant egg hatching inhibition of 98.67%, at 1
mg/ml concentration. In which fruit extracts are used as an anthelmintic in Pheretima posthuma infestation of sheep .
Furthermore, the genus is a rich source of sesquiterpene lactones and flavonoids that might have anthelmintic activity with low
risk of mammalian toxicity</Abstract><Email>Saurabh@gmail.com</Email><articletype>Research</articletype><volume>14</volume><issue>1</issue><year>2024</year><keyword>Artocarpus heterophyllus, Albendazole, Pheretima posthuma, Anthelmintic, Egg Hatch Test</keyword><AUTHORS>Saurabh Khare*, Manisha Tandon, Dr. Nishi Prakash Jain</AUTHORS><afflication>RKDF College of Pharmacy, SRK University-462027, Bhopal, India</afflication></Article></Articles>