43EVALUATION OF IMMUNOMODULATORY ACTIVITY ON PLANT EXTRACTThe aim of the study is to analyze the preliminary phytochemical profile of the extracts of Phyllanthus acidus and Pedalium murex to find out novel immunomodulatory activity of plant extracts from traditionally used medicinal plants and also screening to know their immunomodulatory activity using Swiss albino mice weighing between 18 to 25 kg and the study demonstrates that Phyllanthus acidus and Pedalium murex triggers both specific and non- specific responses to a greater extent, comprised the acute toxicity and preliminary phytochemical screening of both plant extracts, From the results concluding that phytochemical studies the immunostimulant effect of both plants could be attributed to the flavonoid content.sandhyaguggilla9@gmail.comReview412014Phytochemical,Immunomodulatory,ProliferationSandhya Rani G,Alli RameshVaageshwari College of Pharmacy, Thimmapur, Karimnagar Dist.-505481, Andhra Pradesh, India.,Vaageshwari College of Pharmacy, Thimmapur, Karimnagar Dist.-505481, Andhra Pradesh, India.