59TORCH POSITIVE ANTENATAL CASES AT TERTIARY CARE CENTERTORCH stands for Toxoplasama gondii, Rubella virus, Cytomegalovirus (CMV), Herpes simplex virus (HSV). These infections are transmitted transplacentally from mother to fetus. They show vertical transmission of infection. They are grouped together as they evoke similar clinical and pathological manifestations – fever, encephalitis, chorioretinitis, hepatosplenomegaly, pneumonitis, myocarditis and hemolytic anemia. They cause malformation of the embryo by disturbing its development resulting in fetal growth retardation. In the infant they cause mental retardation, cataract, congenital cardiac anomalies and bone defects. Therefore it is necessary to detect these viruses early during pregnancy and manage appropriately. Detection of IgM against the virus is more important than IgG as it indicates recent infection. So this study was planned to find out the number of antenatal case positive for any one of the infections coming under TORCH in a tertiary care hospital. A descriptive study was planned out. The protocol was approved by Institutional Human Ethics Committee. 40 was the estimated sample size. All outpatients who were tested for TORCH infection were included. The data was collected retrospectively. Details on incidence of TORCH positive cases, incidence of each component of TORCH among TORCH positive cases were recorded using case record form. Personal details like, name, Date of Birth, telephone number and address were not taken. Patient details were kept confidential. The collected data was analysed statistically. 15% of the cases were positive for TORCH in suspected cases. It was concluded that 67% were tested positive for CMV and 33% for Toxoplasma. There was no incidence of Rubella/Herpes infection. Toxoplasma infection was treated with Spiramycin. And there is no specific treatment for CMV during pregnancy. All the patients were advised to postpone the pregnancy till the IgM titers come down.bhuvana1421@gmail.comResearch422014TORCH,Pregnancy, Antenatal cases tertiary care centerBhuvaneshwari S,Mekala L,Geetha V. Shastri,Bhuvaneswari KProfessor, Department of Pharmacology, PSG IMS &R, Peelamedu, Coimbatore-641004, Tamilnadu, India.,Former MBBS Student,PSG IMS &R, Peelamedu, Coimbatore-641004, Tamilnadu, India.,Former Professor of Pharmacology, PSG IMS &R, Peelamedu, Coimbatore-641004, Tamilnadu, India.,Professor & HOD of Pharmacology, PSG IMS &R, Peelamedu, Coimbatore-641004, Tamilnadu, India.